| 白血病和MDS患者外周血CA.SCE.CK及超微结构的观察 |
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| 引用本文： | 李静文,毕书增.白血病和MDS患者外周血CA.SCE.CK及超微结构的观察[J].临床与实验病理学杂志,1990,6(1):19-21. |
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| 作者姓名： | 李静文 毕书增 |
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| 作者单位： | 南通医学院病生教研室
(李静文，马建良，贲道锋)，南通医学院电镜室(毕书增) |
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| 摘 要： | 对11例白血病和10例MDS患者外周血进行CA、SCE、CK及电子显微镜观察。结果表明:白血病及MDS患者染色体畸变率及SCE频率增高,细胞增殖周期延长及白细胞超微结构异常等改变具有一致性。这对白血病及MDS的早期诊断提供实验依据。
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| 关 键 词： | 染色体畸变 姊妹染色单体互换 细胞周期动力学 超微结构 骨髓异常增生综合征 |
Studies on CA, SCE, CK, and US of peripheral Blood in Patients with MDS and Leukemia |
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| Li Jingwen et al.Studies on CA, SCE, CK, and US of peripheral Blood in Patients with MDS and Leukemia[J].Chinese Journal of Clinical and Experimental Pathology,1990,6(1):19-21. |
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| Authors: | Li Jingwen |
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| Abstract: | This paper reports our observation on chromosome aberration (CA), sister chromatid exchange (SCE) frequency, cellcycle kinetics(CK)and ultramicrostructure of peripheral blood in patients with myelodysplastic syndrome(MDS)and leukemia. The results were as follows. The chromosome aberrationrate and SCE frequency were increased and the cellcycle kineties were plolonged as well abnormality in ultrastructure were observed in 10 cases of MDS patients and 11 cases of leukemia patients. Above changes are of conformity. The results are of significance and provide experimental basis for early diagnosis of MDS and leukemia. |
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| Keywords: | chromosome aberration(CA) sister chromatid exchange (SCE)cellcyele kinetics(CK) ultramicrostructure ( US ) myelodysplastic syndrome(MDS) |
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