| 同种异体猪胰腺移植后的细胞凋亡形态学观察 |
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| 引用本文： | 时开网,倪绍忠,杨坤兴,张蕴春,樊克武.同种异体猪胰腺移植后的细胞凋亡形态学观察[J].胰腺病学,2006,6(4):201-203. |
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| 作者姓名： | 时开网 倪绍忠 杨坤兴 张蕴春 樊克武 |
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| 作者单位： | [1]江苏南京医科大学附属南京第一医院普外科,南京210006 [2]江苏南京医科大学附属南京第一医院病理科,南京210006 |
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| 基金项目： | 南京市卫生局重点项目（ZKX0216） |
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| 摘 要： | 目的观察胰腺移植后胰腺细胞凋亡的形态学变化。方法以6对动物猪作为实验对象，配对行胰肾联合移植（SPK），观察术后移植物细胞凋亡的形态。结果电镜检查标本可见胰腺细胞出现凋亡，观察到凋亡小体和核固缩现象，TUNEL法标记可观察到大量的凋亡细胞。结论胰腺移植早期可观察到胰腺细胞凋亡现象。
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| 关 键 词： | 胰腺 移植 同种 细胞凋亡 |
| 收稿时间： | 2006-03-21 |
| 修稿时间： | 2006年3月21日 |
Cell apoptosis changes in pork pancreas graft after simultaneous pancreas-kidney transplantation. |
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| SHI Kai-Wang, NI Shao-Zhong, Yang Kun-Xing, ZHANG Yun-Chun, FAN Ke-Wu..Cell apoptosis changes in pork pancreas graft after simultaneous pancreas-kidney transplantation.[J].Chinese JOurnal of Pancreatology,2006,6(4):201-203. |
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| Authors: | SHI Kai-Wang NI Shao-Zhong Yang Kun-Xing ZHANG Yun-Chun FAN Ke-Wu |
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| Institution: | Nanjing First Hospital, Nanjing Medical University. Nanjing 210006, JS, China |
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| Abstract: | Objective To observe the cell apoptosis in pork pancreas graft after simultaneous pancreas-kidney transplantation. Methods Simultaneous pancreas-kidney transplantation was taken in 5 partners of pigs. The cell apoptosis in pancreas graft were observed on the third day after operation. Results Apoptosis bodies and pyknosis in graft pancreatic acinic cell were observed under electron microscope. Cell apoptosis in pancreas graft was detected by using TUNEL. Conclusions Apoptosis can early be observed in pancreas graft after simultaneous pancreas-kidney transplantation. |
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| Keywords: | Pancreas Transplantation homologous Apoptosis |
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