| 壳聚糖在新型给药系统中的应用 |
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| 引用本文： | 张未,潘仕荣. 壳聚糖在新型给药系统中的应用[J]. 药学进展, 2005, 29(9): 404-409 |
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| 作者姓名： | 张未 潘仕荣 |
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| 作者单位： | 中山大学附属第一医院心血管实验室,广东,广州,510080 |
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| 摘 要： | 综述壳聚糖的物理化学和生物特性及在基因转染和不同给药系统中的应用研究近况。壳聚糖作为新型药用辅料,已受到越来越多的关注,对其应用的开发和研究已渗透到药剂学的多个领域。壳聚糖用作非病毒基因载体,也已成为近年来的研究热点之一。它也被广泛研究应用于眼部、鼻腔、口腔、胃内、小肠和结肠等靶向给药载体。
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| 关 键 词： | 壳聚糖 基因载体 靶向给药系统 |
| 文章编号： | 1001-5094（2005）09-0404-06 |
| 收稿时间： | 2005-02-22 |
| 修稿时间： | 2005-02-22 |
Application of Chitosan in Novel Drug Delivery Systems |
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| ZHANG Wei,PAN Shi-rong. Application of Chitosan in Novel Drug Delivery Systems[J]. Progress in Pharmaceutical Sciences, 2005, 29(9): 404-409 |
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| Authors: | ZHANG Wei PAN Shi-rong |
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| Abstract: | The physico-chemical and biological properties of chitosan and its application in gene transfection and varied drug delivery systems were reviewed. Chitosan, a kind of novel pharmaceutical vehicle, as a non-virus gene carrier, has become a hot point in pharmaceutics. It has been studied to be applied to nasal, ophthalmic, buccal, stomach, small intestine and colon targeted drug delivery carriers. |
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| Keywords: | Chitosan Gene carrier Targeted drug delivery system |
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