Assessment of V̇o2peak and Exercise Capacity After Stroke: A Validity Study of the Human Activity Profile Questionnaire |
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| Institution: | 1. Faculty of Medicine and Health, Children''s Hospital at Westmead Clinical School, University of Sydney, Sydney, Australia;2. Kids Rehab, the Children''s Hospital at Westmead, Westmead NSW, Australia;3. Cerebral Palsy Alliance, Discipline of Child and Adolescent Health, The University of Sydney, Sydney, Australia;4. Child Population and Translational Health, the Children''s Hospital at Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia;1. Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense;2. Research Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse;3. Research Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark;4. Department of Clinical Research, University of Southern Denmark, Odense, Denmark;1. Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, the Netherlands;2. GIMBE Foundation, Bologna, Italy;3. Division of Occupational Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;4. Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Bologna, Italy;5. Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy;6. Provincial Agency for Health of the Autonomous Province of Trento, Trento, Italy;7. Department of Clinical Science and Translational Medicine, University of Rome Tor Vergata, Rome, Italy;8. Department of Medicine and Health Science “Vincenzo Tiberio,” University of Molise, Campobasso, Italy;9. Department of Health Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, the Netherlands;10. Department of Epidemiology and Data Science, Amsterdam UMC, Location VUmc, Amsterdam Movement Sciences Research Institute, the Netherlands;11. Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, the Netherlands;1. Physiotherapy Department, Alfred Health, Melbourne, Australia;2. Rehabilitation, Ageing, and Independent Living (RAIL) Research Centre, Monash University, Melbourne, Australia;3. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia;4. Department of Family Practice, University of British Columbia, Vancouver, Canada;5. Department of Physiotherapy, Monash University, Melbourne, Australia;1. Division of Rehabilitation, Kurume University Hospital, Kurume, Fukuoka, Japan;2. Department of Rehabilitation Medicine, University of Kansas Medical Center, Kansas City, Kansas;1. Department of Epidemiology and Biostatistics, School of Public Health, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV;2. Department of Social Medicine, University of North Carolina, Chapel Hill, NC;3. Department of Orthopedics, University of North Carolina, Chapel Hill, NC;4. Department of Epidemiology, University of North Carolina, Chapel Hill, NC, United States |
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| Abstract: | ObjectiveTo investigate the concurrent validity of the Human Activity Profile (HAP) in individuals after stroke to provide the peak oxygen uptake (V?o2peak) and the construct validity of the HAP to assess exercise capacity, and to provide equations based on the HAP outcomes to estimate the distance covered in the Incremental Shuttle Walking Test (ISWT).DesignCross-sectional study.SettingUniversity laboratory.ParticipantsIndividuals (N=57) aged 54±11 years who have experienced stroke.InterventionNot applicable.Main Outcome MeasuresAgreement between the V?o2peak provided by the HAP (lifestyle energy consumption LEC] outcome, in mL/kg?1/min?1) and the criterion standard measure of the V?o2peak (mL/kg?1/min?1), obtained through the symptom-limited Cardiopulmonary Exercise Test (CPET). Correlation between the HAP outcomes (LEC, maximum activity score MAS], and adjusted activity score AAS]) and the construct measure: the distance covered (in meters) in the ISWT. An equation to estimate the distance covered in the ISWT was determined.ResultsHigh magnitude agreement was found between the V?o2peak, in mL/kg?1/min?1, obtained by the symptom-limited CPET and the value of V?o2peak, in mL/kg?1/min?1, provided by the HAP (LEC) (intraclass correlation coefficient, 0.75; P<.001). Low to moderate magnitude correlations were found between the distance covered in the ISWT and the HAP (LEC/MAS/AAS) (0.34≤ρ≤0.58). The equation to estimate the distance covered in the ISWT explained 31% of the variability of the ISWT (ISWTestimated, –361.91+(9.646xAAS)).ConclusionThe HAP questionnaire is a clinically applicable way to provide a valid value of V?o2peak (in mL/kg?1/min?1) and to assess the exercise capacity of individuals after stroke. Furthermore, an equation to estimate the distance covered in the submaximal field exercise test (ISWT) based on the result of the AAS (in points) was provided. |
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