Differences in Cardiometabolic Comorbidities Between Black and White Persons Living With Multiple Sclerosis |
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| Affiliation: | 1. Department of Occupational Therapy, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama;2. School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama;3. Department of Biostatistics, School of Public Health, University of Alabama at Birmingham;1. Institute for Social Medicine and Epidemiology, University of Lübeck, Lübeck;2. Federal German Pension Insurance, Berlin, Germany;1. From the Brain injury Rehabilitation Service, Westmead Hospital, Wentworthville;2. The University of Sydney School of Medicine, Sydney;3. Discipline of Occupational Therapy, Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney;4. Research and Education Network, Westmead Hospital, Wentworthville;5. NHMRC Clinical Trials Centre, The University of Sydney, Sydney, Australia;1. First Affiliated Hospital of Soochow University, Suzhou;2. School of Nursing, Medical College of Soochow University, Suzhou;3. Medical College of Soochow University, Suzhou;4. Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China;1. Department of Rehabilitation, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka;2. Division of Rehabilitation Science, Seirei Christopher University Graduate School, Hamamatsu, Shizuoka;3. Department of Rehabilitation, Hanadaira Care Center, Hamamatsu, Shizuoka;4. Visiting Nurse Station Takaoka, Seirei Care Center Takaoka, Hamamatsu, Shizuoka;5. Department of Rehabilitation, Hamamatsu City Rehabilitation Hospital, Hamamatsu, Shizuoka, Japan;1. Department of Physical Therapy, College of Medical Rehabilitation, Qassim University, Buraidah, Qassim, Saudi Arabia;2. Department of Physical Therapy, El-Sahel Teaching Hospital, General Organization for Teaching Hospitals and Institutes, Cairo, Egypt;3. Department of Physical Therapy for Basic Sciences, Faculty of Physical Therapy, Cairo University, Giza, Egypt;4. Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt;1. Center for Health Assessment Research and Translation (CHART), University of Delaware, Newark, DE;2. Department of Physical Therapy and Psychological, University of Delaware, Newark, DE;3. Department of Brain Sciences, University of Delaware, Newark, DE |
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| Abstract: | ObjectiveTo determine differences in obesity, type 2 diabetes, and hypertension in Black patients compared with White patients with multiple sclerosis (MS).DesignCross-sectional database review.SettingLarge academic medical center research records database.ParticipantsA total of 3191 patient cases (N=3191; 77% female, 34% Black) identified by MS diagnosis within the medical record.InterventionsNot applicable.Main Outcome MeasuresDiagnosis codes for type 2 diabetes and hypertension. Body mass index (BMI), race, age, and sex were collected. Analysis of variance (continuous variables) and chi-square analyses (categorical variables) were conducted to determine differences in obesity, diabetes, and hypertension between race and sex. Logistic regression was conducted to determine odds ratios (ORs) of developing diabetes and hypertension based on race, sex, BMI, and age.ResultsBlack patients were more than twice as likely to be diagnosed as having diabetes (OR, 2.15 [95% CI, 1.70-2.72]; P<.0001) or hypertension (OR, 2.44 [95% CI, 2.05-2.91], P<.0001) compared with White patients. Sex did not present a greater likelihood of being diagnosed as having diabetes; however, men were 1.22 times more likely be diagnosed as having hypertension compared with women (95% CI, 1.01-1.49; P=.0439). Increased age and BMI were also significantly associated with likelihood of diagnosis of diabetes and hypertension (age: diabetes OR, 1.05 [95% CI, 1.04-1.06], P<.0001; hypertension OR, 1.06 [95% CI, 1.05-1.06], P<.0001; BMI: diabetes obese vs normal: OR, 2.11 [95% CI, 1.43-3.11], P=.0002; hypertension: obese vs normal: OR, 1.72 [95% CI, 1.39-2.13], P<.0001).ConclusionsBlack patients with MS are significantly more likely to have cardiometabolic conditions than White patients. These conditions have been associated with poorer health outcomes for people with MS and may have some effect on the differences in MS disease course reported in Black patients. |
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