| Graves病患者131I治疗前后TGAb、TMAb与TPOAb水平变化及其临床观察 |
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| 引用本文： | 李林,廖嘉煦,赵豫琴.Graves病患者131I治疗前后TGAb、TMAb与TPOAb水平变化及其临床观察[J].标记免疫分析与临床,2006,13(4):213-214. |
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| 作者姓名： | 李林 廖嘉煦 赵豫琴 |
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| 作者单位： | 成都市第二人民医院,四川,成都,610017;成都市第六人民医院,四川,成都,610051 |
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| 摘 要： | 通过测定Graves病患者131I治疗前后TGAb、TMAb、TPOAb动态变化,探讨在治疗过程中检测TGAb、TMAb、TPOAb的价值。对73例Graves病患者131I治疗前按TGAb、TMAb、TPOAb水平分为阳性组48例和阴性组25例,并对其治疗后3、6、12和18个月的血清TGAb、TMAb、TPOAb水平进行测量。两组间临床治愈率和未愈率及早发甲低率均有显著性差异(P<0.01)。动态检测Graves病患者131I治疗前后TGAb、TMAb、TPOAb含量变化可以观察疗效、指导治疗、预测复发。
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| 关 键 词： | Graves病 131I治疗 甲状腺球蛋白抗体 甲状腺微粒体抗体 甲状腺过氧化物酶抗体 |
| 文章编号： | 1006-1703(2006)04-0213-02 |
| 收稿时间： | 2006-05-15 |
| 修稿时间： | 2006-07-19 |
Clinlic Observation of TGAb, TMAb and TPOAb Levels in Patients with Graves'Disease Before and After 131I Therapy |
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| LI Lin,LIAO Jia-xu,ZHAO Yu-qin.Clinlic Observation of TGAb, TMAb and TPOAb Levels in Patients with Graves'Disease Before and After 131I Therapy[J].Labeled Immunoassays and Clinical Medicine,2006,13(4):213-214. |
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| Authors: | LI Lin LIAO Jia-xu ZHAO Yu-qin |
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| Abstract: | To determine serum levels of TGAb,TMAb and TPOAb in patients with Graves'disease before and after ~(131)I therapy,and to investigate value of these parameters in treatment,73 patients were divided into positive group and negative group according to TGAb,TMAb and TPOAb levels before ~(131)I treatment.Serum levels of TGAb,TMAb and TPOAb were measured by RIA in two groups before and after treatment 3,6,12,18 months respectively.There were significant diferences between two groups(P<0.01).The measurement of TGAb,TMAb and TPOAb levels in patients with Graves'disease was beneficial to monitor treatement and predict prognosis. |
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| Keywords: | Graves'disease ~(131)I therapy TGAb TMAb TPOAb |
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