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| 山生柳多糖的免疫增强作用 | |
| 引用本文： | 封士兰,陈立仁,孟彦,党月兰. 山生柳多糖的免疫增强作用[J]. 中药药理与临床, 2001, 17(4): 23-25 |
| 作者姓名： | 封士兰 陈立仁 孟彦 党月兰 |
| 作者单位： | 1. 中国科学院兰州化学物理研究所,兰州,730000 2. 甘肃省卫生学校 3. 兰州医学院 |
| 基金项目： | 甘肃省1999年中青年科技研究基金YS991-A23-021,通信联系人 |
| 摘 要： | 目的：研究山生柳多糖的免疫作用。方法：给小鼠ig山生柳多糖，测定胸腺重量、脾脏重量、炭粒廓清指数、血清抗SRBC抗体效价、血清溶血素、T淋巴细胞和淋巴细胞转化率。结果：山生柳多糖使小鼠胸腺和脾脏重量明显增加；增加单核吞噬细胞的吞噬能力；提高血清抗SRBC抗体凝集效价；血清溶血素含量明显增加；外周血中T淋巴细胞百分比明显增加；淋巴细胞转化率提高。结论：山生柳多糖对小鼠的非特异性和特异性免疫具有明显增强作用。 |
| 关 键 词： | 山生柳多糖 免疫增强 T淋巴细胞 淋巴细胞转换率 |
The Immune-enhancing Effect of Salix Oritrepha Polysaccharide |
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| Feng Shilan,Meng Yan ,Dang Yuelan ,Chen Liren. The Immune-enhancing Effect of Salix Oritrepha Polysaccharide[J]. Pharmacology and Clinics of Chinese Materia Medica, 2001, 17(4): 23-25 | |
| Authors: | Feng Shilan Meng Yan Dang Yuelan Chen Liren |
| Affiliation: | Feng Shilan,Meng Yan 1,Dang Yuelan 2,Chen Liren |
| Abstract: | Objective: To study the immunity of Salix oritrepha. Methods: The Solution of Salix oritrepha polysaccharide in water was administered to mouse in order to determine weights of thymus and spleen of mouse, carbolic particle clearance index, antibody titer of serum against SRBC, serum hemolysin, T lymphocytes rate and lymphocyte transformation rate. Results: Salix oritrepha polysaccharide could increase weights of thymus and spleen of mouse, enhance phagocytic power of mononuclear phagocyte and increase antibody agglutination titer of serum against SRBC, the content of serum hemolysin has been increased apparently. The T lymphocytes percentage in peripheral blood and lymphocyte transformation rate has been also increased. Conclusions: Salix oritepha polysaccharide has apparent enhancement specific immunity and non specific immunity in mouse. |
| Keywords: | Salix oritrepha polysaccharide immune enhancing effect |
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