儿童急性白血病688例发病情况流行病学调查

目的通过单中心小样本研究，发现我国部分地区儿童急性白血病（AL）发病在季节上的差异性。方法对2003年10月至2006年6月就诊于中国医学科学院血液病医院的688例初诊儿童AL患儿的发病情况进行回顾性分析：结果儿童AL在夏季和冬季以及每年1月和6月存在季节性发病高峰。结论初步了解我国北方地区儿童AL的季节性发病趋势，提示儿童AL与感染的相关性。

Epidemiologic study of 688 acute leukemia in children:a single centre retrospective analysis

Objective To find out some trigger factors for the onset of acute childhood leukemia by examining seasonal distribution through a small cohort study in a single center.Methods The records of 688 childhood patients(age≤15 years)whom were initially diagnosed at Blood Disease Hospital of CAMS from October 2003 to June 2006,were retrospectively analyzed.Results In terms of time,our study provides modest support for sessonal peaks in summer and winter,or in Jan & Jun.Conclusion We initially realized the season tendency of the onset of acute childhood leukemia in some northern parts of China.which suggest that childhood acute leukemia is associated with the infection.