平阳霉素治疗口腔颌面部血管瘤56例临床分析

目的 探讨平阳霉素(PYM)治疗口腔颌面部血管瘤临床效果.方法 同顾性分析我院自2000年5月-2002年5月采用PYM瘤内注射治疗口腔颌面等部位的各种类型血管瘤56例患者的临床资料.结果 56例患者随访6个月～6年.治愈27例(48.2%),基本治愈20例(35.7%),好转6例(10.7%),无效3例(5.4%);17例出现发热反应,对症处理后体温均降至正常;12例出现厌食,1～2 d后症状消失,局部破溃15例,过敏性休克1例,经抢救治愈,未出现肺炎样变及肺纤维化等并发症.结论 PYM局部注射治疗血管瘤疗方法 简便、疗效显著、疗程短、副作用小.治愈后无瘢痕,在临床有重要应用价值.

Clinical analysis of 56 cases of oral and maxillofacial hemangioma treated with Bleomycin

Objective To investigate the effects of Pingyangmycin (PYM) on oral and maxillofacial hemangioma. Methods The clinical data of 56 patients with various types of oral and maxillofacial hemangioma that were treated with PYM intratumoral injection in our hospital from May 2000 to May 2002 were retrospectively analysis. Results 56 patients were followed up for 6 months to 6 years. All of them, 27 cases (48.2%) were cured, 20 cases (35.7%) basical cure, 6 cases (10.7%) were improved, 3 cases (5.4%) were ineffective, 17 cases had fever response, 12 cases had anorexia for 1-2 days. 15 cases had partial rupture, 1 cases occurred anaphylactic shock. Conclusion The method of PYM local injection for treatment of oral and maxillofacial hemangioma is simple, effective, short period of treatment, and less side effects and scarring.