Effects of Artemisia pallens Wall. on blood glucose levels in normal and alloxan-induced diabetic rats |
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| Affiliation: | 1. Division of Ethnopharmacology, Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram District, Pin-695 562, Kerala, India;2. Division of Ethnomedicine, Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram District, Pin-695 562, Kerala, India;1. Laboratory of Math and Complex Systems, Ministry of Education, School of Mathematical Sciences, Beijing Normal University, Beijing 100875, PR China;2. School of Mathematical Sciences, Beijing Normal University, Beijing 100875, PR China;1. Department of Urology, Mayo Clinic, Rochester, Minnesota;2. Department of Radiology, Mayo Clinic, Rochester, Minnesota;3. Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota;1. Global Government Affairs, Herbalife Nutrition, 800 West Olympic Blvd., Suite 406, Los Angeles, CA 90015, USA;2. Purdue University, 700 West State St., West Lafayette, IN 47907, USA;3. Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St., Boston, MA 02111, USA;4. Washington University School of Medicine, 660 South Euclid Ave, St. Louis, MO 63110, USA;5. Council for Responsible Nutrition, 1828 L St, NW, Suite 510, Washington, DC, 20036, USA;1. Department of Health Sciences, Faculty of Science, University of Mauritius, Réduit, Mauritius;2. School of Healthcare Science, Manchester Metropolitan University, Manchester M1 5GD, United Kingdom;1. Department of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan;2. Department of Plant Bio-technology, Faculty of Biotechnology, Vietnam National University of Agriculture, Trau Quy crossing, Gia Lam district, Hanoi, Vietnam;3. Department of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan;4. Department of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok, Thailand;5. Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan;6. Department of Veterinary Surgery and Reproduction, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Trau Quy crossing, Gia Lam district, Hanoi, Vietnam;7. Department of Internal Medicine and Pharmacology, Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Trau Quy crossing, Gia Lam district, Hanoi, Vietnam |
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| Abstract: | Oral administration of the methanol extract of the aerial parts of Artemisia pallens Wall. (used in Indian folk medicine for the treatment of diabetes mellitus) led to significant blood glucose lowering effect in glucose-fed hyperglycaemic and alloxan-induced diabetic rats. This effect of the extract was dose dependent and significant at 100 mg/kg level in glucose-fed rats. In fasted normal rats, the extract caused a moderate hypoglycaemic effect at a higher dose (1000 mg/kg). The water extract (1000 mg/kg) was inactive. |
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