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Sequential occurrence of benign partial epilepsy and childhood absence epilepsy in three patients
Affiliation:1. Department of Neurology, University of Illinois, Chicago, IL;2. Department of Medical Education, Northwestern University, Feinberg School of Medicine, Chicago, IL.;3. Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL.;4. Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL.;5. Department of Emergency Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL.;1. Department of Clinical Neurophysiology, MIRA, Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands;2. Department of Neurology, Rijnstate Ziekenhuis, Arnhem, The Netherlands;3. Dept of Neurology and Clinical Neurophysiology, Medisch Spectrum Twente, Enschede, The Netherlands;1. Department of Neurology, University of Nevada School of Medicine, Reno, NV, United States;2. Department of Neurology, Mayo Clinic, Jacksonville, FL, United States;3. Department of Neurology, Mayo Clinic College of Medicine and Health Sciences, Jacksonville, FL, United States
Abstract:We first report 3 patients who experienced absence epilepsy (mean age at onset: 6.3 years; range: 4–9) 1–4 years after recovering from an electroclinical picture characteristic of benign childhood partial epilepsy (BCPE). All patients were put on monotherapy with sodium valproate, and their long-term course was excellent with remission of absences and normalization of EEG recordings. The exceptionality of our observation favors the hypothesis that BCPE and absence epilepsy are distinct entities.
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