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18F-FDG PET/CT in pancreatic adenocarcinoma: A role at initial imaging staging?
Authors:M Wartski  A Sauvanet
Institution:1. Department of Nuclear Medicine, Université de Paris – Paris Descartes, Cochin Hospital-AP–HP, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France;2. Department of Hepato-Pancreato-Biliary Surgery, Pôle des Maladies de l’Appareil Digestif, Université de Paris-Paris Diderot, Beaujon Hospital, 92110 Clichy, France
Abstract:Pancreatic ductal adenocarcinoma represents 90% of all pancreatic tumors. The only hope for prolonged survival in patients with this condition still remains surgery with complete R0 resection. Initial imaging has a pivotal role to identify patients who are eligible to curative surgery and those who may benefit of neoadjuvant chemotherapy. This review provides an analysis of the recent literature on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in pancreatic adenocarcinoma. Performances of FDG PET in the detection of lymph node involvement and metastatic spread at initial staging and those in the assessment of response to treatment are described.
Keywords:Corresponding author    Pancreatic adenocarcinoma  18F-Fluorodeoxyglucose positron emission tomography (FDG PET/CT)  Imaging
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