The influence of CaMKII and ERK phosphorylation on BDNF changes observed in mice selectively devoid of CREB in serotonergic or noradrenergic neurons期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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The influence of CaMKII and ERK phosphorylation on BDNF changes observed in mice selectively devoid of CREB in serotonergic or noradrenergic neurons

Authors:	Katarzyna Rafa-Zab?ocka Grzegorz Kreiner Monika Bagińska Irena Nalepa

Institution:	Department of Brain Biochemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland

Abstract:

Keywords:	Corresponding author BDNF brain derived neurotrophic factor BCA bicinchoninic acid BSA bovine serum albumin CaMKII Ca2+/calmodulin-dependent protein kinase II CREB cyclic AMP response element binding?protein CREM cyclic AMP response element modulator DBH dopamine β-hydroxylase DMI desipramine ERK extracellular signal-regulated kinase ER estrogen receptor ERT2 mutant estrogen ligand-binding domain FLX fluoxetine GAPDH glyceraldehyde 3-phosphate dehydrogenase HIP hippocampus KO knock out LC locus coeruleus MAP mitogen-activated protein kinase PFC prefrontal cortex RIPA radioimmunoprecipitation assay buffer RN raphe nuclei SAL saline SSRI selective serotonin reuptake inhibitor TPH tryptophan hydroxylase-2 TrkB tropomyosin receptor kinase B TST tail suspension test BDNF CREB Desipramine Fluoxetine Noradrenergic system Serotonergic system
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