阿托伐他汀对冠状动脉血流缓慢患者冠状动质血流储备和血小板聚集率的影响

目的探讨阿托伐他汀对冠状动脉血流缓慢患者冠状动脉血流储备和血小板聚集率的影响。方法选择100例冠状动脉血流缓慢患者作为研究组，随机分为干预组和无干预组各50例，另选健康者50例为对照组，检验各组冠状动脉血流储备和血小板聚集率。结果治疗8周后，干预组治疗前后与无干预组和对照组超声心动图各指标比较（P〉0．05），干预组最大冠状动脉扩张CFV显著升高，静息状态CFV显著降低，CFR显著升高，与无干预组差异均有统计学意义（P〈0．05）。干预组血脂紊乱显著改善（P〈0．05），干预组PAl、PA2、PA3水平显著下降，与无干预组差异均有统计学意义（P〈0．05）。结论阿托伐他汀不仅能显著改善患者血脂紊乱，还能显著改善冠状动脉血流缓慢患者冠状动脉血流储备和血小板聚集率。

Atorvastatin on coronary arteries slow blood flow in patients with coro- nary flow reserve and platelet aggregation rate

Objective To investigate the atorvastatin slow coronary blood flow in patients with coronary flow reserve and platelet aggregation rate. Methods All of 100 cases of patients with slow coronary flow for the study group were randomly divided into intervention group and non-intervention group, 50 patients, alternative health, 50 cases of the control group and test groups coronary flow reserve and platelet aggregation rate. Results After 8 weeks of treatment, intervention before and after treatment with the non-intervention group and the control group ultrasound echocardiog- raphy diagram of each index comparison （P 〉 0.05）, intervention group＇s largest coronary dilatation CFV significantly with elevated resting state CFV significantly with reducing, CFR significantly with elevated, with the non-intervention group differences were statistically significant （P 〈 0.05）. The the dyslipidemia intervention group significantly im- proved （P 〈 0.05） was significantly lower in the intervention group PAl, PA2, PA3 level with the non-intervention group differences were statistically significant （P 〈 0.05）. Conclusion Atorvastatin statins not only significantly im- prove blood lipid disorders, can significantly improve slow coronary blood flow in patients with coronary flow reserve and platelet aggregation rate.