白魔芋精粉对荷瘤小鼠的抑瘤和免疫增强作用

方法：用２５、５０、１００ｍｇ／ｋｇ白魔芋精粉（ＡＡＰ）对Ｓ１８０、ＥＡＣ、Ｈｅｐｓ和Ｕ１４四瘤株进行了动物移植性肿瘤的抑瘤试验。结果：ＡＡＰ对Ｓ１８０、ＥＡＣ、Ｈｅｐｓ和Ｕ１４的抑瘤率分别为５９．７４％、５４．０２％、５２．７９％和４０．８６％。ＡＡＰ能显著增强荷瘤小鼠单核巨噬细胞的吞噬功能，与对照组相比，差异极显著（Ｐ＜０．０１），Ｔ淋巴细胞转化能力也显著高于对照组（Ｐ＜０．０１），肿瘤相伴免疫试验显示ＡＡＰ治疗组的长瘤率与瘤重均明显小于对照组

ANTITUMOR AND IMMUNOENHANCEMENT ACTIVITY OF AMORPHOPHALLUS ALBUS REFINED POWDER ON NEOPLASM BEARING MICE

The antitumor and immunoenhancement activity in neoplasm bearing mice of Amorphophallus albus,a refined powder(AAP)product from amorphophallus albus tuber was studied.The inhibitory rates of AAP(25mg/kg,ig)on S 180 ,EAC,Heps,U 14 were 57.94%, 54.02%, 52.22%, 40.86% respectively.Compared with the control,the phagocytic function of mononuclear macrophage and the T lymphocyte proliferation of EAC bearing mice treated with AAP were increased significantly(P<0.01).The tumor number and weight of concomitant tumor immunity test groups were decreased greatly(P<0.01).It suggested that AAP could augment cellullar immune action and inhibit tumor growth in neoplasm bearing mice.