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TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma |
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| Authors: | Chen Jingkao Dou Yunling Zheng Xiaoke Leng Tiandong Lu Xiaofang Ouyang Ying Sun Huawei Xing Fan Mai Jialuo Gu Jiayu Lu Bingzheng Yan Guangmei Lin Jun Zhu Wenbo |
| Affiliation: | 1.Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, People’s Republic of China ;2.School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, People’s Republic of China ;3.Department of Anesthesiology, Department of Pathology and Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China ;4.Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA, 30329, USA ;5.Department of Pediatrics, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, People’s Republic of China ;6.South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center and Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China ;7.Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY, 11794-8480, USA ; |
| Abstract: | Tumor Biology - The melastatin-like transient receptor potential 7 (TRPM7) has been implicated in proliferation or apoptosis of some cancers, indicating the potential of TRPM7 as an anti-anaplastic... |
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