肝硬化病人消化性溃疡和门脉高压性胃病的发生及特点

目的 研究肝硬化病人消化性溃疡和门脉高压性胃病的发生及临床特点。方法 以1990年1月－1999年4月间在我院住院的496例病人为研究对象作胃镜检查。结果 肝硬化消化性溃疡的发生率为14．92％，门脉高压性胃病的发生率为43．75％；在childA级、B级、C级肝功能病人之间消化性溃疡和门脉高压性胃病的发生率差异无显著意义（P＞0．05）；有门脉高压性胃病和食道静脉曲张者消化性溃疡的发生率明显高于无门脉高压性胃病和食道静脉曲张者（P＜0．01）。肝硬化病人消化性溃疡82．43％无症状。结论 门静脉高压可能是肝硬化病人消化性溃疡发生率增高的重要致病因素，肝硬化病人消化性溃疡绝大多数无症状。

Peptic ulcer and portal hypertensive gastrosis in patients with liver cirrhosis

Objective To investigate the occurrence and clinical characteristics of peptic ulcer and portal hypertensive gastrosis in patients with liver cirrhosis.Methods A retrospective investigation was performed in 496 inpatients with liver cirrhosis from January 1990 to April 1999 who have been examined by gastroscope.Results The incidence of peptic ulcer in cirrhosis patients was 14.92%, and portal hypertensive gastrosis was 43.75%. The incidences of peptic ulcer and portal hypertensive gastrosis showed that no statistical differences between patients with child's A, child's B and child's C ( P >0.05). The incidences of peptic ulcer in patients with portal hypertensive gastrosis (21.20%) and esophageal varices (16.71%) were markedly higher than that in patients without portal hypertensive gastrosis (10.04%) and esophageal varices (7.37%) (P<0.01). 82.43% of peptic ulcer in the patients with liver cirrhosis were asymptomatic.Conclusion Portal hypertension is an important pathogenic factor in high prevalence of peptic ulcer in cirrhostic patients. The most of cirrhotic patients with peptic ulcer is asymptomatic.