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Quantitation of hemoglobin A1c: a rapid, automated precision-chromatography technique.
Authors:H Wajcman  B Dastugue  D Labie
Affiliation:1. Institut de Pathologie Moléculaire, 24, rue du Faubourg Saint-Jacques, 75014 ParisFrance;2. Laboratoire de Biochimie Médicale, Faculté de Médecine, Place Henri-Dunant, 63001 Clermont-Ferrand Cedex France
Abstract:Hemoglobin A1c is increased in patients with diabetes mellitus and its level reflects the status of blood glucose equilibrium over a period of several weeks. The practical use of its estimation was hampered by technical difficulties in investigating large series of samples. In order to apply this examination for routine purposes we describe in this paper acceleration and full automatization of the original chromatographic method allowing quantitation of hemoglobin A1c in 45 min.
Keywords:To whom correspondence should be addressed.
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