Effect of pancreatic lipase on supramolecular DNA complexes in eukaryotic cellsin vivo andin situ |
| |
| Authors: | V A Struchkov N B Strazhevskaya |
| |
| Institution: | (1) Laboratory of Cell Metabolism, N. N. Blokhin Oncology Research Center, Russian Academy of Medical Sciences, Moscow |
| |
| Abstract: | Effect of pancreatic lipase on supramolecular DNA complexes, nuclear matrix, and 70% ethanol-fixed cells is studied by elastoviscosimetry.
It is shown that lipase induces DNA degradation not onlyin vitro but also in whole cells. Possible role of neutral lipids, in particular, DNA-bound diglycerides, in the arrangement of chromosomal
DNA is discussed.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 12, pp. 635–639, December, 1997 |
| |
| Keywords: | supramolecular DNA complexes nucleotides eukaryotic cells lipase degradation |
| 本文献已被 SpringerLink 等数据库收录！ |
|
