Does persistent organic pollutant PFOS (perfluorooctane sulfonate) negative impacts on the aquatic invertebrate organism,Astacus leptodactylus [Eschscholtz, 1823]

Highly persistent perfluorooctane sulfonate (PFOS) is an industrial fluorinated organic chemical with significant bioaccumulation and biomagnification properties. The purpose of this study was to determine the toxic effects of sublethal PFOS on the aquatic invertebrate organism, narrow-clawed crayfish [Astacus leptodactylus Eschscholtz, 1823]. The 96?h LC₅₀ value was determined as 48.81?mg/L (34.19–63.68?mg/L) with probit analysis. The sublethal experimental design was formed into four groups solvent control (DMSO, dimethyl sulphoxide), non-treated control group, and 1/10 (5?mg/L) and 1/100 (0.5?mg/L) of 96?h LC₅₀ of PFOS, and crayfish were exposed for 48?h, 7?d, and 21?d under laboratory conditions. Total haemocyte counts (THCs) decreased, while the haemolymph total antioxidant status (TAS) values increased (p?p?p?>?0.05). GPX and CAT activities decreased, but SOD activity increased in hepatopancreas tissue (p?A. leptodactylus is a reliable model for examining histopathological alterations and differences in enzyme activities together with the haemolymph findings in toxicology studies amid aquatic species.