不同ABO血型下肢闭合骨折后下肢深静脉血栓形成的发生率分析

目的:探讨不同ABO血型患者下肢闭合骨折后下肢深静脉血栓形成（DVT）发生率的差异。方法:回顾性研究2014年8月至2018年6月西安交通大学医学院附属红会医院创伤骨科收治的1 951例下肢骨折患者，男924例，女1 027例；年龄中位数为63（46, 78）岁（16~102岁）。按照血型分组：O型组572例，A型组5...

Deep vein thrombosis after closed fracture of lower extremity and blood types ABO

Objective To investigate the differences in incidence of deep vein thrombosis(DVT)after closed fracture of lower extremity between patients with different blood types ABO.Methods A retrospective study was conducted in the 1,951 patients who had been admitted to Department of Orthopaedics Trauma,Honghui Hospital Affiliated to Xi'an Jiaotong University for lower extremity fractures from August 2014 to June 2018.They were 924 males and 1,027 females with a mean age of 63(46,78)years(range,from 16 to 102 years).Of them,572 were type O,564 type A,609 type B and 206 type AB.Venous ultrasonography was performed on both lower extremities within 12 hours after admission.The incidences of DVT after fracture were compared between different blood types in all the patients,patients with proximal fracture of the knee,peri-knee fracture and distal fracture of the knee,and patients<60 years old and≥60 years old.Results The incidences of DVT were,respectively,26.75%(153/572),28.72%(162/564),34.32%(209/609)and 29.61%(61/206)for patients with blood type O,type A,type B and type AB.The DVT incidence for type B was significantly higher than that for type O(P<0.008).The incidences of DVT were,respectively,28.74%(98/341),28.99%(100/345),39.45%(144/365)and 30.97%(35/113)for blood type O,type A,type B and type AB in the patients with proximal fracture of the knee.The DVT incidence for blood type B was significantly higher than those for blood type O and blood type A(P<0.008).There were no significant differences in the DVT incidence between different blood types ABO in the patients with peri-knee fracture,distal fracture of the knee,<60 years old or≥60 years old(P>0.05).The incidences of DVT were,respectively,30.99%(97/313),33.33%(108/324),45.22%(156/345),34.74%(33/95)for blood type O,type A,type B and type AB in the patients≥60 years old.The DVT incidence for blood type B was significantly higher than those for blood type O and blood type A(P<0.008).Conclusions The incidence of DVT varied with different blood types ABO after lower extremity fracture.The highest DVT incidence was found in patients with blood type B.The impact of blood type on the DVT incidence after lower extremity fracture was mainly observed in the patients with proximal fracture of the knee or an age of≥60 years old.