关注和解释疗法对化疗期胃肠道肿瘤患者疲乏及睡眠质量的影响

目的探讨关注和解释疗法对化疗期胃肠道肿瘤患者疲乏及睡眠质量的效果。方法2018年12月至2019年12月选择宁夏某两所三级甲等医院住院的胃肠道肿瘤患者84例为研究对象。按随机数字表法分对照组和观察组各42例,两组患者均进行常规治疗,观察组在此基础上,接受10周的关注和解释疗法。干预前、干预10周时及干预完成后3个月,采用肿瘤患者疲乏量表及匹兹堡睡眠指数量表(Pittsburgh sleep quality index,PSQI)进行评定。采用SPSS 17.0软件进行统计分析,组间比较采用独立样本t检验及重复测量方差分析。结果(1)两组疲乏总分及各维度得分时间效应、组间效应及交互效应均显著(P<0.01)。进一步作简单效应分析,干预后10周及干预完成后3个月,对照组与观察组患者疲乏总分及各维度得分均差异有统计学意义(均P<0.01)。(2)两组在PSQI总分、睡眠质量、入睡时间、睡眠时间、睡眠障碍得分时间效应、组间效应及交互效应均显著(P<0.01),睡眠效率、日间功能障碍及催眠药物使用得分方面时间效应、组间效应及交互效应均不显著(P>0.05)。进一步作简单效应分析,干预后10周PSQI总分(6.83±2.46)分,(10.79±1.01)分;睡眠质量(1.00±0.22)分,(1.24±0.82)分;入睡时间(0.91±0.26)分,(1.40±0.86)分;睡眠时间(1.00±0.20)分,(2.02±0.72)分;睡眠障碍(0.79±0.22)分,(1.60±0.59)分]及干预完成后3个月,对照组与观察组患者PSQI总分、睡眠质量、入睡时间、睡眠时间、睡眠障碍得分比较,均差异有统计学意义(均P<0.01)。结论关注和解释疗法能有效缓解胃肠道肿瘤患者化疗期间的疲乏,进而改善睡眠质量。

Effects of attention and interpretation therapy on fatigue and sleep quality in patients with gastrointestinal tumor during chemotherapy

Objective To investigate the effects of attention and interpretation therapy on fatigue and sleep quality in patients with gastrointestinal tumor during chemotherapy.Methods From December 2018 to December 2019,eighty-four patients with gastrointestinal tumor hospitalized in two hospitals(third-grade class-A)in Ningxia were selected as the research objects.According to the random number table,they were divided into the control group and the observation group with 42 cases in each group.Patients in the two groups received routine care.On this basis,the observation group received 10 weeks of attention and interpretation therapy.Cancer patients fatigue scale and Pittsburgh sleep quality index(PSQI)scale were used to evaluate before intervention,10 weeks after intervention and 3 months after intervention.SPSS 17.0 software was used for statistical analysis.Independent sample t-test and repeated measure analysis of variance were used for comparison between groups.Results(1)The time effect,inter group effect and interaction effect of fatigue total scores and each dimension score of the two groups were significant(all P<0.01).Further simple effect analysis showed that there were significant differences in the total score and each dimension score of fatigue between the control group and the observation group at 10 weeks after intervention and 3 months after intervention(all P<0.01).(2)The time effect,inter group effect and interaction effect of PSQI total score,sleep quality,sleep time,sleep disorder score were significant(all P<0.01),but the time effect,inter group effect and interaction effect of sleep efficiency,daytime dysfunction and hypnotic drug use score were not significant(all P>0.05).Further simple effect analysis showed that there were significant differences in PSQI total score,sleep quality,sleep time,sleep time and sleep disorder scores between the control group and the observation group 10 weeks after the intervention(PSQI total score(6.83±2.46)vs(10.79±1.01);sleep quality(1.00±0.22)vs(1.24±0.82);sleep time(0.91±0.26)vs(1.40±0.86);sleep time(1.00±0.20)vs(2.02±0.72);sleep disorder(0.79±0.22)vs(1.60±0.59))and 3 months after the intervention(all P<0.01).Conclusion Attention and interpretation therapy can effectively alleviate the fatigue of gastrointestinal tumor patients during chemotherapy,and improve sleep quality.