重症监护病房呼吸机相关性肺炎的病原学分布和临床分析

目的:了解重症监护病房(ICU)呼吸机相关肺炎(VAP)发生率、病原菌分布情况和预防措施。方法:回顾分析我院2002年5月至2006年4月使用呼吸机的115例患者中出现45例VAP患者的临床资料、病原菌分布以及药敏结果。结果:115例机械通气患者中有45例发生了VAP,VAP发生率为39.1%,病死率为33.3%。共分离出病原菌206株,革兰氏阴性杆菌154株占74.8%,革兰氏阳性菌54株占21.4%,真菌8株占8.9%,结论:革兰氏阴性杆菌是重症监护病房呼吸机并发肺部感染的主要致病菌,临床医师可根据药敏试验合理选用抗菌素。

Pathogenic Distribution and Clinical Analysis of Ventilator Associated Pneumonia in Intensive Care Unit

Objective: To understand the formation rate of ventilator associated pneumonia in intensive care unit,pathogenetic distribution and prevent measure.Method: We retrospectively analyzed clinical material,pathogenetic distribution and antibiotic susceptibility data of 45 cases used ventilator from May,2002 to April,2006.Result: 45 patiens developed VAP among 115 used mechanical ventilation.its development rate is 39.1%.The mortality rate is 33.3%.We altogether separates 206 kinds of pathogenic germ.G negative bacillus is 154.it accounts for 74.8%.G positive bacteria is 54.It accounts for 21.4%.Fungus is 8,It accounts for 8.9%.Conclusion: G negotive bacillus is main pathogetic germ of ventilator associated pneumonia in ICU.CLinical doctors may choice antibiotics reasonably according to drug susceptibility test.