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盐酸美沙酮口服液的稳定性研究
引用本文:林彩,董慧.盐酸美沙酮口服液的稳定性研究[J].华西药学杂志,1997,12(4):233-234.
作者姓名:林彩  董慧
作者单位:第三军医大学西南医院!重庆,630038,第三军医大学西南医院!重庆,630038,第三军医大学西南医院!重庆,630038,第三军医大学西南医院!重庆,630038,第三军医大学西南医院!重庆,630038
摘    要:用HPLC测定盐酸美沙酮口服液的含量,平均回收率为100.17%,RSD〈1%。用补均速法进行稳定性实验,在室温下贮存3.8年;光照对其含量有一定的影响。

关 键 词:盐酸美沙酮  口服液  稳定性  美沙酮  高效液相色谱

STABILITY OF METHADONE HYDROCHLORIDE ORAL SOLUTION
Lin Cai,Dong Hui,Dai Qing, Ma Wenxiu, Liu Songqing.STABILITY OF METHADONE HYDROCHLORIDE ORAL SOLUTION[J].West China Journal of Pharmaceutical Sciences,1997,12(4):233-234.
Authors:Lin Cai  Dong Hui  Dai Qing  Ma Wenxiu  Liu Songqing
Abstract:To establish a HPLC method for determining the concentration of Methadone Hydrochloride oral solution, the average recovery was 100. 17%. The RSD for the inter and intra-day were all less than 1%. The stability of the Methadone Hydrochloride oral solution was investigated by initial average rate method. The results showed that the experimental date of Methadone Hydrochlloride oral solution is 3. 8 years. The concentration of Methadone Hydrochloride is reduced by light irradiation.
Keywords:Methadone Hydrochloride oral solution Initial average rate method Stability HPLC
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