某部队官兵幽门螺杆菌感染情况的调查

目的了解部队官兵胃病患病及幽门螺杆菌(Hp)感染情况,并寻求一种可靠的应用于Hp感染流行病学调查的方法。方法应用细菌培养法、荧光抗体方法、直接涂片法、Hp诊断卡4种方法对242名官兵的胃液、口腔牙菌斑进行Hp检测,并与临床调查结果及血清学方法相比较。胃液采集采用胶囊采样法。结果临床调查242名官兵患胃病人数为62人(25.2%)。血清学方法检测Hp感染率为35.5%。4种方法胃液Hp检出率分别为7.43%、21.9%、28.1%、17.4%;口腔牙菌斑中Hp检出率分别为5.79%、32.2%、66.9%、42.6%。几种方法中以荧光抗体法与临床复合率最好。结论应用荧光抗体法检测牙菌斑Hp可作为流行病学调查的方法使用,而荧光抗体结合胶囊采样法检测胃液Hp作流行病学调查发现并确认现胃病患者,是一种很有前途的方法。

Investigation on the infection rate of Helicobacter pylori infection in military officers and soldiers

To investigate the infection rate of Helicobactert pylori infection in military officers and soldiers and to seek out a reliable method to be used for the epidemiological survey of infection with Hp,the Hp in the gastric fluids and dental plaques of 242 military officers and soldiers were detected by means of bacterial cultures,fluorescent antibody assay,direct smear examination and Hp diagnosis card method.The capsule method was used to obtain the gastric fluids and the results to detect the presence of Hp were compared with the clinical data and the serological findings.It was found that the incidence of gastritis in these 242 subjects for study was 25.6%(62/242),in which the detection rates of Hp in gastric fluids with the four method of detection mentioned above were 7.43%,21.9%,28.1% and 17.4% respectively,and the detection rates of Hp in dental plaques with these 4 methods were 5.79%,32.2%,66.9% and 42.6% respectively.The infection rate of HpWTBZ] detected by the serological method was 35.5% and the results of fluorescent antibody assay correlated closely with the clinical data.It is concluded that detection of Hp in dental plaques by fluorescent antibody assay can be used in the epidemiological survey.