Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers

Authors:	Véronique?Garambois,Fabienne?Glaussel,Elodie?Foulquier,Marc?Ychou,Martine?Pugnière,Robin?X?Luo,Binyam?Bezabeh,André?Pèlegrin author-information" > author-information__contact u-icon-before" > mailto:APelegrin@valdorel.fnclcc.fr" title=" APelegrin@valdorel.fnclcc.fr" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author

Affiliation:	1.INSERM, EMI0227 Centre de Recherche en Cancérologie,CRLC Val d'Aurelle-Paul Lamarque,Cedex 5 Montpellier,France;2.CNRS UMR 5160,Montpellier,France;3.Abgenix, Inc,Fremont,USA

Abstract:	Background Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human anti-CEA MAbs.

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