| 均匀试验设计优选产妇康颗粒挥发油的包合工艺 |
| |
| 引用本文： | 贾永艳,祝侠丽,周红敏,李九席,魏超娟,李翠萍,田效志.均匀试验设计优选产妇康颗粒挥发油的包合工艺[J].中国实验方剂学杂志,2012,18(12):34-37. |
| |
| 作者姓名： | 贾永艳 祝侠丽 周红敏 李九席 魏超娟 李翠萍 田效志 |
| |
| 作者单位： | 河南中医学院,郑州,450008 |
| |
| 基金项目： | 郑州市科技攻关项目(064SGDS33221-3) |
| |
| 摘 要： | 目的:优化产妇康颗粒中挥发油的β-环糊精包合工艺.方法:采用饱和水溶液法包合,以挥发油包合率为指标,以β-环糊精与挥发油的比例、包合温度、包合时间为考察因素,采用均匀试验优选包合工艺,并对包合物的物相进行验证.结果:最佳工艺为挥发油与β-CD的比例1∶8,包合温度40℃,包合时间140 min.在该优选条件下,挥发油包含率达75％,验证结果显示包合物已形成.结论:该优选的包合工艺合理、稳定、可行.
|
| 关 键 词： | 产妇康颗粒 挥发油 β-环糊精包合 均匀试验设计 |
| 收稿时间： | 2011/12/26 0:00:00 |
Optimization of Inclusion Technology for Volatile Oil from Chanfukang Granule by Uniform Design |
| |
| JIA Yong-yan,ZHU Xia-li,ZHOU Hong-min,LI Jiu-xi,WEI Chao-juan,LI Cui-ping and TIAN Xiao-zhi.Optimization of Inclusion Technology for Volatile Oil from Chanfukang Granule by Uniform Design[J].China Journal of Experimental Traditional Medical Formulae,2012,18(12):34-37. |
| |
| Authors: | JIA Yong-yan ZHU Xia-li ZHOU Hong-min LI Jiu-xi WEI Chao-juan LI Cui-ping and TIAN Xiao-zhi |
| |
| Institution: | Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China;Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China |
| |
| Abstract: | Objective:To optimize inclusion process of volatile oil from Chanfukang granule.Method: Inclusion process was carried out by saturated aqueous solution method,inclusion process was optimized by uniform design with inclusion ratio of volatile oil as index,taking ratio of volatile oil to β-CD,inclusion temperature and inclusion time as factors,and physical phase of inclusion complex was verified.Result: Optimum inclusion process was as follows:ratio of volatile oil to β-CD 1∶8,inclusion temperature 40 ℃,inclusion time 140 min.Inclusion rate of volatile oil was as high as 75% under these optimized technology conditions.Validation result showed that inclusion compound had been formed.Conclusion:This optimized inclusion process was reasonable,stable and feasible. |
| |
| Keywords: | Chanfukang granule volatile oil β-cyclodextrin inclusion uniform test |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
|
