Prevalence and determinants of restless leg syndrome in type 2 diabetes mellitus (T2DM) in Pakistan |
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Authors: | Muhammad Shahzad Nawaz Muhammad Sarfraz Nawaz Kifayat-Ullah Shah Zia ul Mustafa Ali Ahmed Hafiz Sajjad Ahmed Tahir Mehmood Khan Allah Bukhsh Salamat Ali |
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Institution: | 1. Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan;2. Department of Pharmacy, Punjab University College of Pharmacy, AllamaIqbal Campus, University of the Punjab, 54000, Lahore, Pakistan;3. Capital Authority Hospital Islamabad, Pakistan;4. School of Pharmacy, Monash University, Jalan Lagoon Selatan, 47500, Bandar Sunway Selangor DarulEhsan, Malaysia;5. Institute of Pharmaceutical Sciences, University of Veterinary and Animal Science, Lahore, Pakistan;6. District Head Quarter (DHQ) Hospital, Pakpattan and Punjab University Lahore, Pakistan |
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Abstract: | Background and aimsRestless legs syndromes (RLS) are intrinsic sleeping disorder and its prevalence rate is 10–15% in general population but it is observed that prevalence rate is different in diabetes patients. Current study aims to find prevalence and determinants of RLS in people living with type 2 diabetes mellitus in Pakistan.MethodA multicenter cross-sectional observational study was conducted in 388 diabetes patients attending daily diabetes clinics and teaching hospitals in Pakistan’s twin city between August 2019 and February 2020. The chi-square test and linear regression were used to detect RLS-related factors in type 2 diabetes mellitus.ResultsThe prevalence of RLS found was; 3.1% patients with diabetes were suffering from very severe RLS, 23.5% from severe RLS, 34% from moderate RLS, 21.1% from mild RLS and 18.3% from non-RLS. Gender, age, education, blood glucose fasting (BSF), blood glucose random (BSR) and HBA1c were found to be significant predictors of RLS in patients with diabetes.ConclusionPolicy makers can develop local interventions to curb the growing RLS prevalence by keeping in control the risk factors of RLS in people living with type 2 diabetes. |
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Keywords: | Diabetes Blood glucose fasting (BSF) Blood glucose random (BSR) HbA1c Pakistan |
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