| Abstract: | This review explores the pathophysiology associated with anovulation which affects 30% of cases of infertility. It provides an overview of the evidence based management of different groups of anovulation including role of adjuvant therapies. Anovulation can be effectively managed with induction of ovulation, the aim of which is to restore normal physiological ovulatory function. Weight optimization is the cornerstone of management in functional hypogonadotropic hypogonadism and polycystic ovarian syndrome (PCOS). The aim is to achieve monofollicular development, minimizing the risk of ovarian hyperstimulation and multiple pregnancies. The holistic approach involves induction of ovulation along with health education regarding lifestyle modifications and need for long term hormone replacement therapy in appropriate cases. |
