降钙素原和C反应蛋白在新型冠状病毒肺炎中的表达及其对预后评估价值

目的 探讨降钙素原和C反应蛋白（CRP）在新型冠状病毒肺炎（COVID-19）病人血清中的表达及其预后评估价值。方法选取2020年2—3月四川绵阳四0四医院收治的119例COVID-19病人进行研究，回顾性分析病人临床资料，血清降钙素原、CRP水平及预后生存状况，将临床分型为轻型、普通型的病人列为轻度组（93例），重型、危重型的病人列为重度组（26例），依据病人住院30 d预后生存状况分为存活组（112例）、死亡组（7例）。采用免疫放射法检测血清降钙素原水平，采用散射比浊法检测血清CRP水平，并进行组间比较，采用logistic回归模型分析影响COVID-19病人预后因素。结果 轻度组与重度组相比，性别、发热、咳嗽、腹泻、乏力、头痛均差异无统计学意义（P>0.05），与轻度组相比，重度组年龄、高血压、糖尿病、冠心病、慢性阻塞性肺疾病、呼吸困难比例、血清降钙素原[（0.52±0.11）μg/L比（0.13±0.03）μg/L]、CRP水平[（62.53±13.26）mg/L比（15.91±2.79）mg/L]均较高（P<0.05）；与存活组相比，死亡组血清降钙素原[1.01(...

Expressions of procalcitonin and C-reactive protein in the serum of patients with COVID-19 and its prognostic value

Objective To investigate the expressions of procalcitonin and C reactive protein (CRP) in serum of patients with coronavi. rus pneumonia (COVID-19) and their prognostic values.Methods A total of 119 patients with COVID-19 who were admitted to Sichuan Mianyang 404 Hospital from February 2020 to March 2020 were studied, the clinical data, levels of serum procalcitonin, C-reactive pro.tein and prognosis were retrospectively analyzed, and the patients with clinical classification of mild and common types were classified asmild group (93 cases), and the patients with severe and critical type were classified as severe group (26 cases), according to the prognosis