前列腺癌术后RapidArc与IMRT放疗计划的剂量学比较

目的 比较前列腺癌术后辅助放疗患者RapidArc与适形调强放疗(IMRT)计划在靶区和危及器官的剂量学差异。方法 选择2020年7月至2022年2月在安徽医科大学第一附属医院接受术辅助放疗或者术后生化复发的前列腺癌患者14例，分别设计7野IMRT和RapidArc计划，对2种计划的靶区和危及器官的剂量学进行比较。结果 RapidArc计划的D_2%为(6 645.28±242.48)cGy,低于IMRT计划，差异具有统计学意义(P<0.05)。D_2%的下降导致RapidArc计划的靶区剂量均匀度指数优于IMRT计划(P<0.05);RapidArc计划的膀胱V₄₀和V₅₀,直肠V₅₀以及左右侧股骨头D_5%均低于IMRT计划，差异有统计学意义(P<0.05)。RapidArc计划的执行效率高于IMRT计划，差异有统计学意义(P<0.05)。结论 RapidArc计划在在靶区剂量均匀度，危及器官高剂量受照体积限制，以及机器跳数和治疗时间...

Dosimetry comparison study between RapidArc and IMRT planning for postoperative prostate cancer

Objective To compare the dosimetry differences between RapidArc and IMRT plan for patients diagnosed with prostate cancer.Methods Fourteen prostate cancer patients received post-prostatectomy or biochemical relapse radiotherapy therapy in the First Affiliated Hospital of Anhui Medical University were selected for this study. We designed RapidArc and IMRT plan for each prostate cancer patient respectively, and the dosimetric differences in target area and organs at risk (OAR) between RapidArc and IMRT was assessed.Results The D_2% of RapidArc (6 645.28±242.48 cGy)was significantly lower than that of seven-field plan, and the difference was statistically significant (P<0.05), resulting inbetter homogeneity index. The bladder V₄₀, V₅₀ and rectum V₅₀ and bilateral femoral head D_5% of RapidArc were obviously reduced than those of IMRT plan (P<0.05). In addition, the execution efficiency of RapidArc was significantly higher than that of IMRT plan (P<0.05). Conclusions RapidArc is superior to IMRT in terms of dose homogeneity of target volume, protection of organs at risk at high dose, machine unit number and treatment time.