Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis |
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| Authors: | Omid Asbaghi Faezeh Fouladvand Michael J. Gonzalez Damoon Ashtary-Larky Razieh Choghakhori Amir Abbasnezhad |
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| Affiliation: | 1. Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran;2. School of Public Health, Department of Human Development, University of Puerto Rico Medical Sciences Campus, Puerto Rico;3. Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran;4. Razi Herbal Medicines Research Center, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran;5. Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran |
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| Abstract: | Background and aimsSeveral studies have investigated the potential beneficial effects of green tea in patients with type 2 diabetes mellitus (T2DM). Therefore, we aimed to perform a systematic review and meta-analysis of the randomized controlled trials (RCTs) that assessed the effect of supplementary intake of green tea on fasting plasma glucose (FPG), fasting insulin, hemoglobin A1c (HbA1c) and HOMA-IR in patients with T2DM.MethodsA systematic search was performed in Web of Science, PubMed and Scopus without any language and time restriction up to June 2019, to retrieve the related RCTs. Meta-analysis was carried out using both the random and fixed effects model where appropriate. I2 index was used to evaluate the heterogeneity.ResultsInitial search yielded 780 publications. Fourteen articles were eligible. Our meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM.ConclusionResults of the present systematic review and meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM. |
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| Keywords: | Fasting plasma glucose Insulin Hemoglobin A1c HOMA-IR Green tea Type 2 diabetes meta-Analysis |
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