Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis |
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Authors: | Christine Dierkes Boris Ehrenstein Sylvia Siebig Hans-J?rg Linde Udo Reischl and Bernd Salzberger |
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Institution: | (1) Department of Internal Medicine I, University Hospital Regensburg, 93042 Regensburg, Germany;(2) Institute of Medical Microbiology and Hygiene, University of Regensburg, 93042 Regensburg, Germany |
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Abstract: | Background Timely identification of pathogens is crucial to minimize mortality in patients with severe infections. Detection of bacterial
and fungal pathogens in blood by nucleic acid amplification promises to yield results faster than blood cultures (BC). We
analyzed the clinical impact of a commercially available multiplex PCR system in patients with suspected sepsis. |
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