华北耧斗菜的化学成分研究

 目的 研究华北耧斗菜(Aquilegia yabeana Kitag中的化学成分。方法 利用Diaion HP-20、Toyopearl HW-40、硅胶柱等柱色谱技术进行分离纯化，根据化合物的理化性质和光谱数据鉴定结构。 结果 分离并鉴定了13化合物的结构，分别为：3，4-二羟基苯乙酸(Ⅰ， 羟基酪醇(Ⅱ，邻苯二酚(Ⅲ，对羟基苯乙醇(Ⅳ， 3-甲氧基-4-羟基苯乙醇(Ⅴ， 原儿茶酸(Ⅵ， 没食子酸(Ⅶ， 5，7，4′-三羟基-8-C-β-D-葡萄糖黄酮碳苷(Ⅷ， 5，4′-二羟基-6，7-二甲氧基-8-C-β-D-葡萄糖黄酮碳苷(Ⅸ， 5，7，4′-三羟基-6-甲氧基-8-C-β-D-葡萄糖黄酮碳苷(Ⅹ， 5，7，8，4′-四羟基-6-C-β-D-葡萄糖黄酮碳苷(Ⅺ， 槲皮素-3-O-β-D-木糖-(1→2-β-D-半乳糖苷(Ⅻ， 芦丁(ⅩⅢ。 结论 以上13个化合物均为首次从本植物中分离得到。

Study on Chemical Constituents of Aquilegia yabeana Kitag

OBJECTIVE To study the chemical constituents of Aquilegia yabeana Kita. METHODS The compounds were isolated by Diaion HP-20， Toyopearl HW-40， and silical gel column chromatography. The structures of these compounds were identified by physiochemical properties and spectral analysis. RESULTS Thirteen compounds were obtained， and their structures were identified as 3， 4-dihydroxyphenyl acetic acid (Ⅰ， hydroxytyrosol (Ⅱ， pyrocatechol (Ⅲ， 4-hydroxyphenethyl alcohol (Ⅳ， 4-hydroxy-3-methoxyphenylethanol (Ⅴ， protocatechuic acid (Ⅵ， gallic acid (Ⅶ， 8-β-D-galactopyranosyl-5， 7， 4′-trihydroxyflavone (Ⅷ， 5， 4′-dihydroxy-6， 7-dimethoxy-8-C-β-D-glucopyranosylflavone (Ⅸ， 5， 7， 4′-trihydroxy-6-methoxy-8-C-β-D-glucopyranosyl flavone (Ⅹ， 6-β-D-galactopyranosyl-5， 7， 8， 4′-tetrahydroxyflavone (Ⅺ， quercetin-3-O-β-D-xylopyranosyl-(1→2-β-D-galactopyranoside (Ⅻ， and rutin (ⅩⅢ. CONCLUSION All the compounds were isolated from this plant for the first time.