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PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function |
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| Authors: | Zhenying Shang Chenxi Li Xuemei Liu Manhong Xu Xiaomin Zhang Xiaorong Li Colin J. Barnstable Shaozhen Zhao Joyce Tombran-Tink |
| Affiliation: | 1.Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China;2.Department of Neural and Behavioral Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States;3.Department of Ophthalmology, Penn State College of Medicine, Hershey, Pennsylvania, United States |
| Abstract: | |
| Keywords: | cornea corneal nerves tear lacrimal gland meibomian gland trigeminal ganglion corneal sensitivity MAPK pathway ERK1/2 AKT corneal epithelium PEDF knockout neurotrophic factors: NGF BDNF NT-3 GDNF EGF PEDF receptors: laminin receptor ATGL PLXDC1 PLXDC2 LRP6 |