| 睾丸Leydig细胞干细胞研究进展 |
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| 引用本文： | 张思孝,董强.睾丸Leydig细胞干细胞研究进展[J].中华男科学杂志,2005,11(11):803-805. |
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| 作者姓名： | 张思孝 董强 |
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| 作者单位： | 四川大学华西医院泌尿外科,四川,成都,610041 |
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| 摘 要： | Leyd ig细胞是机体合成和分泌雄激素的主要细胞,利用Leyd ig细胞干细胞的体外定向诱导分化扩增至具有雄激素合成功能的成熟细胞再植入机体中,对雄激素缺乏的治疗具有非常广阔的临床应用前景。
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| 关 键 词： | Leydig细胞 雄激素 干细胞 |
| 文章编号： | 1009-3591（2005）11-0803-03 |
| 收稿时间： | 2005-08-30 |
| 修稿时间： | 2005年8月30日 |
Progress in the Study of Stem Leydig Cells |
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| ZHANG Si-xiao,DONG Qiang.Progress in the Study of Stem Leydig Cells[J].National Journal of Andrology,2005,11(11):803-805. |
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| Authors: | ZHANG Si-xiao DONG Qiang |
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| Institution: | Department of Urology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China. |
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| Abstract: | Leydig cells are the primary source of testosterone.As is true for all specialized cells,Leydig cells originally arise from primitive undifferentiated stem cells,stem Leydig cells(SLCs).The huge potential of SLCs is to be used therapeutically to restore testosterone levels in males with androgen deficiency due to diverse causes.The initial paradigm for cell therapy would call for harvesting the SLCs of an androgen deficient male,amplifying these cells in vitro,inducing differentiation in vitro,and then implanting the mature Leydig cells back into the same individual.Natl J Androl,2005,11(11):803-805 |
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| Keywords: | Leydig cell testosterone stem cell |
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