Measurement of the secretion of technetium-99m hexamethylpropylene amine oxime into breast milk |
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Authors: | D S C Marshall N R Newberry P J Ryan |
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Institution: | (1) Department of Nuclear Medicine, Medway Hospital, Windmill Road, ME7 5NY Gillingham, Kent, UK |
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Abstract: | There are no published data for the activity of technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) found 1in breast milk. The amount of radioactivity in breast milk following the administration of 500 MBq99mTc-HMPAO for a brain perfusion study has been measured. The effective dose to the infant was calculated to be 0.26 mSv, so necessitating no interruption of breast feeding. Unbound99mTc is readily secreted into breast milk and the effective dose will remain less than 1 mSv if the99mTc-HMPAO labelling effici ency is 99% for the worse reported case, and could remain <1 mSv for the mean reported case for99mTc-HMPAO labelling efficiencies down to 94%. |
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Keywords: | Breast milk Hexamethylpropylene amine oxime Labelling efficiency Technetium |
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