Hepatitis B vaccination in infants of mothers infected with human immunodeficiency virus |
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Authors: | M P Arrazola J R De Juanes A J Aragn A Garcia de Codes J T Ramos |
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Institution: | M. P. Arrazola,J. R. De Juanes,A. J. Aragón,A. Garcia de Codes,J. T. Ramos |
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Abstract: | A study was conducted to investigate the immunogenicity of a recombinant DNA hepatitis B vaccine in neonates and children of HIV-infected women. Immunization against hepatitis B consisted of three 10 μg doses of the vaccine administered on a 0-, 1- and 6-month schedule. The children were followed up for an average of 11 months. Of the 118 HIV-positive neonates who participated in the study, 95 lost their HIV antibodies during the follow-up period. Most (94.2%) of the latter who completed the study responded to the vaccine. Of the 23 who remained HIV-positive, 17 completed the study and 7 produced hepatitis B antibodies. © 1995 Wiley-Liss, inc. |
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Keywords: | vaccine hepatitis B perinatal HIV transmission infants |
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