用核磁共振新技术测定日本续断皂甙E1的结构

从日本续断Dipsocus japunicus Miq.根的乙醇提到物中得到一个新三萜皂甙(5糖甙)，命名为日本续断皂甙E₁(japondipsaponin E₁)。用化学方法及¹HNMR,¹³CNMR,¹H-¹H COSY，一维多重接力COSY，选择性远程DEPT和三重共振NOE差谱等方法，鉴定其结构为3-O-α-L-吡喃鼠李糖(1-3)-β-D-吡喃葡萄糖（1→3）-α-L-吡喃鼠李糖（1→2）-α-L-吡喃阿拉伯糖常春藤皂甙元28-O-β-D-吡喃葡萄糖甙。

APPICATION OF NEW TECHNIQUES OF NMR IN THE STRUCTURE ELUCIDATION OF JAPONDIPSAPONIN E1 ISOLATED FROM DIPSACUS JAPONICUS Miq.

A new triterpenoid saponin, named japondipsaponin E₁ (5 sugars), was isolated from the ethanolic extract of the roots of Dipsacus japonicus Miq. The structure was elucidated by chemical and spectral methods. e. g. ¹HNMR, ¹³CNMR, ¹H-¹H COSY, selective long range DEPT and NOEDS, to be 3-O-α-L-rhamnopyranosyl(l→3)-β-D-glucopyranosyl (l→3)-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-hederagenin 28-O-β-D-glucopyranoside.