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脂肪干细胞成骨分化的研究进展
引用本文:刘琴,陈芳,王丽平,张宜.脂肪干细胞成骨分化的研究进展[J].实验动物与比较医学,2017,25(5):581-586.
作者姓名:刘琴  陈芳  王丽平  张宜
作者单位:中国人民解放军武汉总医院医学实验科,武汉 430070,中国人民解放军武汉总医院医学实验科,武汉 430070,中国人民解放军武汉总医院医学实验科,武汉 430070,中国人民解放军武汉总医院医学实验科,武汉 430070
摘    要:随着骨组织工程研究取得较好的发展,涌现出各类种子细胞。脂肪干细胞,来自脂肪组织,具有诸多的优势,成为骨组织工程研究的热点种子细胞之一。本文综述了脂肪干细胞成骨分化的诱导方法、过程、验证方法、影响成骨分化的供体因素和实验因素,并对其未来研究方向进行了展望。

关 键 词:组织工程  脂肪干细胞  成骨分化
收稿时间:2017/2/16 0:00:00

Research progress on osteogenic differentiation of adipose-derived stem cells
LIU Qin,CHEN Fang,WANG Li-ping and ZHANG Yi.Research progress on osteogenic differentiation of adipose-derived stem cells[J].Laboratory Animal and Comparative Medicine,2017,25(5):581-586.
Authors:LIU Qin  CHEN Fang  WANG Li-ping and ZHANG Yi
Institution:Department of Medical Experiments, Wuhan General Hospital of Chinese People''s Liberation Army, Wuhan 430070, China,Department of Medical Experiments, Wuhan General Hospital of Chinese People''s Liberation Army, Wuhan 430070, China,Department of Medical Experiments, Wuhan General Hospital of Chinese People''s Liberation Army, Wuhan 430070, China and Department of Medical Experiments, Wuhan General Hospital of Chinese People''s Liberation Army, Wuhan 430070, China
Abstract:With the good progress of bone tissue engineering, various kinds of seed cells have emerged. Adipose derived stem cells (ASCs) have many advantages, and become one of the hot seed cells in bone tissue engineering. This review focused on their induction method, induction process and verification method, and the donor factors and experimental factors affecting the osteogenic differentiation were summarized. We also looked forward the future research interest of ASCs'' osteogenic differentiation.
Keywords:Tissue engineering  Adipose-derived stem cells  Osteogenic differentiation
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