| GAS41在神经胶质瘤中的表达 |
| |
| 引用本文： | 杨俊梅,王光伟,黄亮,熊元元,刘志雄,刘运生,何铁勇,向双林,张健. GAS41在神经胶质瘤中的表达[J]. 湖南师范大学学报(医学版), 2012, 9(2): 4-7 |
| |
| 作者姓名： | 杨俊梅 王光伟 黄亮 熊元元 刘志雄 刘运生 何铁勇 向双林 张健 |
| |
| 作者单位： | 湖南师范大学医学院;湖南师范大学生命科学院;中南大学湘雅医院神经外科 |
| |
| 基金项目： | 湖南师范大学青年优秀人才培养计划资助项目(ET81006) |
| |
| 摘 要： | 目的:探讨GAS41在神经胶质瘤中的表达及意义。方法:收集不同等级新鲜胶质瘤标本30例,用免疫组化染色法检测GAS41基因在这些标本中的表达情况。结果:GAS41在人高级别神经胶质瘤(III,IV级)中表达水平明显高于低级别神经胶质瘤(I,II级)(P<0.05)。结论:GAS41在神经胶质瘤中的表达水平随着肿瘤恶性程度的增高而增强,提示GAS41的表达量可以作为高级别神经胶质瘤的一个判断标准。
|
| 关 键 词： | GAS41 神经胶质瘤 表达 |
The Expression of GAS41 in Gliomas |
| |
| Yang Junmei,#,Wang Guangwei,#,Huang Liang,Xiong Yuanyuan,Liu Zhixiong,Liu Yunsheng,He Tieyong,Xiang Shuanglin,Zhang Jian. The Expression of GAS41 in Gliomas[J]. Journal of Hunan Normal University(Medical Science), 2012, 9(2): 4-7 |
| |
| Authors: | Yang Junmei # Wang Guangwei # Huang Liang Xiong Yuanyuan Liu Zhixiong Liu Yunsheng He Tieyong Xiang Shuanglin Zhang Jian |
| |
| Affiliation: | 1.Medical College,Hunan Normal University,Changsha 410013,China;2.College of Life Sciences,Hunan Normal University,Changsha 410081,China;3.Department of Neurosurgery,Xiangya Hospital,Central South University,Changsha 410008,China) |
| |
| Abstract: | Objective To explore the relationship between the expression of gliomas amplified sequence 41(GAS41) and grading of human glioma.Methods Thirty fresh gliomas specimens of different grades were collected.The expression of GAS41 was detected by immunohistochemical staining.Results The expression of GAS41 in the high-grade gliomas specimens(grade III,grade IV)was significantly higher than that in the low-grade(grade I,grade II)(P<0.05).Conclusion The expression of GAS41 in gliomas is enhanced with the increasing degree of malignancy,and it is suggested that the expression of GAS41 may be used as a judging criterion of the high grade gliomas. |
| |
| Keywords: | GAS41 Gliomas Expression |
| 本文献已被 CNKI 等数据库收录！ |
|
