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MicroRNAs与胃癌关系研究进展
引用本文:周颀,蒋敬庭,吴昌平. MicroRNAs与胃癌关系研究进展[J]. 国际免疫学杂志, 2012, 35(5): 341-345
作者姓名:周颀  蒋敬庭  吴昌平
作者单位:213003常州,苏州大学附属第三医院肿瘤生物诊疗中心,常州市医学生物技术重点实验室
基金项目:基金项目:国家自然科学基金资助项目(81171653,30972703);江苏省卫生厅医学科技发展基金项目(P200932,P200933)
摘    要:MicroRNAs是一类内源性非编码RNA,近年来研究发现,若干microRNAs参与基因调控,直接参与胃癌的发生和分化,microRNAs表达谱与胃癌的进展和预后等密切相关.因此,microRNAs的研究对于阐明胃癌相关基因的功能和胃癌癌变的分子机制具有重要的意义.

关 键 词:微小RNA  胃癌  基因调控

Research progress in association of microRNAs and gastric cancer
ZHOU Qi , JIANG Jing-ting , WU Chang-ping. Research progress in association of microRNAs and gastric cancer[J]. International Journal of Immunology, 2012, 35(5): 341-345
Authors:ZHOU Qi    JIANG Jing-ting    WU Chang-ping
Affiliation:. Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Abstract:MicroRNAs are endogenous non-coding RNAs. Recent studies indicated that a number of microRNAs are directly involved in the genetic regulation related with the occurrence and differentiation of gastric cancer. Expression profiles of microRNA in gastric cancer are closely associated with progress and prognosis. Thus, studies of mieroRNAs are of great significance to clarify the functions of gastric cancer-related genes and the carcinogenesis of gastric cancer.
Keywords:MicroRNAs  Gastric cancer  Genetic regulation
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