Genistein,a potent inhibitor of secretory phospholipase A2: a new insight in down regulation of inflammation |
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Authors: | Kattepura K. Dharmappa Riyaz Mohamed Holenarasipura V. Shivaprasad Bannikuppe Sannanaik Vishwanath |
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Affiliation: | (1) Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysore, 570006, India; |
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Abstract: | Objectives Some of the legumes, spices and medicinal herbs rich in genistein are known for their anti-inflammatory properties. Anti-inflammatory property of these herbs is determined by subjecting secretory phospholipase A2 (sPLA2) inhibition, a key enzyme in the inflammatory reactions by genistein. |
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