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赛庚啶和西咪替丁联合治疗慢性荨麻疹的双盲观察43例
引用本文:卢勇田. 赛庚啶和西咪替丁联合治疗慢性荨麻疹的双盲观察43例[J]. 中国新药与临床杂志, 1991, 0(1)
作者姓名:卢勇田
作者单位:陕西省渭南地区医院皮肤科 渭南
摘    要:针对人体皮肤血管处存在H_1和H_2受体,联合采用H_1和H_2受体阻滞剂即赛庚啶2mg和西咪替丁400 mg tid睡前加服1次,疗程1mo治疗慢性荨麻疹43例,治愈率为51%,总有效率达95%,与安慰剂进行双盲对照有非常显著差异。作者认为联合用药比单用任何一种更为有效、安全。

关 键 词:赛庚啶/治疗应用  西咪替丁/治疗应用  荨麻疹/药物疗法  联合药物疗法

Cyproheptadine and cimetidine in combination for chronic urticaria in 43 patients by double-blind test
LU Yong-Tian. Cyproheptadine and cimetidine in combination for chronic urticaria in 43 patients by double-blind test[J]. Chinese Journal of New Drugs and Clinical Remedies, 1991, 0(1)
Authors:LU Yong-Tian
Abstract:Among 184 patients of chronic urticaria, 43 of them received cyprohepta-dine 2mg and cimetidine 400mg qid for 1 mo, 64 received cyproheptadine 2mg alone, 47 received cimetidine 400mg alone while 30 patients placebo only. The cure rates were 51%, 20%, 6%, and 0%, respectively. The response rates were 95%, 81%, 70% and 7%, respectively. This illustrates that the combination therapy is better than the others.
Keywords:cyproheptadine/therapeutic use  cimetidine/therapeutic use  urticaria/ drug therapy  combination   drug therapy  
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