吉兰-巴雷综合征患者神经电生理检测结果分析

目的：探讨吉兰-巴雷综合征(GBS)患者的神经电生理特点。方法：对25例GBS患者进行肌电图(EMG)、运动神经传导速度(MCV)、F波及感觉神经传导速度(SCV)检测，共检测126条运动神经、89条感觉神经及57块肌肉，并对结果进行分析。结果：上、下肢神经远端潜伏期延长占53．2％，MCV减慢占70．6％，F波异常占92．0％，SCV减慢占64．0％，EMG提示神经源性改变占68．4％。结论：GBS为广泛的周围神经损害，存在以脱髓鞘为主伴有轴索变性的神经电生理改变。神经电生理检测对GBS的诊断是极为重要的诊断手段。

Analysis of electroneurophysiological detection in patients with Guillain-Barre syndrome

Objective:To explore the electroneurophysiological characteristics in patients with Guillain-Barre syndrome (GBS).Methods:EMG,MCV,SCV,and F wave were determined in 25 patients with GBS diagnosed clinically.A total of 126 motor nerves,89 sensory nerves and 57 muscles were detected.Results:In the 126 motor nerves examined ,prolongation of the distal latency was found in 53.2%,reduction of MVC in 70.6%,F waves abnomality was noted in 92.0%,reduction of SCV in 64.0%,EMG revealed neurogenic changes in 68.4%.Conclusion:.GBS might result in widespread peripheral nerve damages.The dominant electroneurophysiological changes might show peripheral nerve demyelination accompanied by axone degeneration.The electroneurophysiological detection might be the very important method for diagnosing GBS.