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糖尿病患者中链和长链甘油三酯乳剂的清除比较
引用本文:姜朝晖,张利华,李令堂,徐薇.糖尿病患者中链和长链甘油三酯乳剂的清除比较[J].中国临床营养杂志,1996(1).
作者姓名:姜朝晖  张利华  李令堂  徐薇
作者单位:南京军区南京总医院 210002杭州市解放军一一七医院(姜朝晖),南京军区南京总医院 210002(张利华,李令堂),南京军区南京总医院 210002(徐薇)
摘    要:比较胰岛素非依赖性糖尿病患者中/长链甘油三酯(MCT/LCT)混合乳剂和长链甘油三酯(LCT)乳剂的清除率。每组各6例,在4小时输入脂肪期间,MCT/LCT组血甘油三酯达稳定状态。动力学参数表明MCT/LCT乳剂有着明显较小的表观分布容积和较短的半衰期。两种乳剂对血糖浓度也有不同的影响。在葡萄糖和脂肪代谢紊乱时,如需行含脂肪的肠外营养,应优先选择MCT/LCT混合乳剂。

关 键 词:糖尿病  脂肪乳剂

Comparision of clearance rates of MCT/LCT and LCT emulsion in Diabetics
Jiang Chaohui,et al..Comparision of clearance rates of MCT/LCT and LCT emulsion in Diabetics[J].Chinese Journal of Clinical Nutrition,1996(1).
Authors:Jiang Chaohui  
Abstract:I In noninsulin-dependent diabetics with slightly elevated triglyceride levels, clearance rates of infused medium chain triglyceride/long chain triglyceride(MCT/LCT) and long chain triglyceride(LCT) emulsions were compared. There were six patients in each group. During 4 hr lipid infusion, serum triglyc-erides reached a steady state triglyceride levels were seen only with MCT/LCT. Kinetics paramtetrs were also computed, showing significantly smaller apparent volume of distribution and shorter high-life value in MCT/LCT than in LCT. There were also different effects on serum glucose concentration with both emul-sions. According to these data, if needed, parenteral nutrition with lipids in states of disturbed glucose and lipid metabolism may preferentially be done with MCT/LCT emulsion.
Keywords:Diabetics hsellitus Fat emulsion
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