| 羟氯喹治疗对视网膜电图的影响 |
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| 引用本文： | 傅东红,邹耀红,俞可佳,史惠琴,高恺言.羟氯喹治疗对视网膜电图的影响[J].现代预防医学,2011,38(9):1748-1749,1751. |
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| 作者姓名： | 傅东红 邹耀红 俞可佳 史惠琴 高恺言 |
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| 作者单位： | 江苏省无锡市人民医院眼科,无锡,214023 |
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| 摘 要： | 目的]通过观察视网膜电图(ERG)变化,评估羟氯喹(HCQ)对视网膜损害。方法]对45例系统性红斑狼疮、类风湿性关节炎和原发性干燥综合症用HCQ治疗的患者进行为期1年的前瞻性研究。在服药前后分别进行视力、视野、眼底和ERG的检查并给予比较。结果]治疗期间视力,眼底和视野的检查均无异常。但有3位患者分别在服药3个月和6个月时出现了ERG的a波和b波振幅下降。结论]ERG能较早的观察到HCQ对视网膜的毒性,对视功能损伤有早期诊断价值。
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| 关 键 词： | 羟氯喹 视功能 视网膜电图 |
EFFECT OF THE HYDROXYCHLOROQUINE TRERTMENT ON ELECTRORETINOGRAM |
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| FU Dong-hong,ZOU Yao-hong,YU Ke-jia,et al..EFFECT OF THE HYDROXYCHLOROQUINE TRERTMENT ON ELECTRORETINOGRAM[J].Modern Preventive Medicine,2011,38(9):1748-1749,1751. |
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| Authors: | FU Dong-hong ZOU Yao-hong YU Ke-jia |
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| Institution: | FU Dong-hong,ZOU Yao-hong,YU Ke-jia,et al.(Wuxi People's Hospital,Wuxi 214023,China) |
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| Abstract: | Objective]To evaluate damage of retinal function in patients receiving hydroxychloroquine(HCQ) through observing the changes of the electroretinogram(ERG) .Methods]A prospective study was performed for 45 patients with systemic lupus erythematosus,rheumatoid arthritis and primary Sjgren's syndrome treated with HCQ therapy.The patients were followed-up for 12 months.Visual acuity,visual field and fundus examination as well as ERG were compared before and after taking medicine.Results]The visual acuity,vis... |
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| Keywords: | Hydroxychloroquine Visual function Electroretinogram |
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