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| 麦迪霉素高产菌株的筛选 | |
| 引用本文： | 韩威,熊宗贵,贾美茹,王明芳. 麦迪霉素高产菌株的筛选[J]. 沈阳药科大学学报, 1990, 0(3) |
| 作者姓名： | 韩威 熊宗贵 贾美茹 王明芳 |
| 作者单位： | 沈阳药学院微生物制药教研室，沈阳药学院微生物制药教研室，沈阳药学院微生物制药教研室，沈阳药学院 微生物制药专业51期学生 |
| 摘 要： | 通过紫外线和紫外线-咖啡因对生米加链霉菌1748变株进行处理,筛选出5株产麦迪霉素高产菌株。经紫外线照射40sec和50sec并加500μg/ml咖啡因处理所产生的变异菌株比原株产量提高30%,且稳定。我们还研究了变异菌株的形态与产量的关系。 |
| 关 键 词： | 生米加链霉菌 诱变 麦迪霉素 |
SELECTION OF HIGH YIELDING STRAINS OF MIDECAMYCIN |
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| Han Wei,Xiong Zonggui,Jia Meiru,Wang Mingfang. SELECTION OF HIGH YIELDING STRAINS OF MIDECAMYCIN[J]. Journal of Shenyang Pharmaceutical University, 1990, 0(3) | |
| Authors: | Han Wei Xiong Zonggui Jia Meiru Wang Mingfang |
| Affiliation: | Han Wei,Xiong Zonggui,Jia Meiru,Wang Mingfang,Department of Microbial pharmaceutics |
| Abstract: | Through the mutation of Streptomyces mycarofaciens var. 1748 by UV or UV-caffeinc, five high yielding strains were seleted. UV irradn, for 40 and 50 sees and500 μg/ml caffeine produced mutants raising production of midecamvcin than the or-iginal strain, by 30% and these mutants were stable in production. The relationshipbetween the morphology of mutants and their productivity was also studied. |
| Keywords: | Streptomyces mycarofaciens Mutation Midecamyein |
| 本文献已被 CNKI 等数据库收录！ | |