Studieson the inhibition of the growth of KB cells by 9- and 7-(keto-nucleosides) |
| |
| Authors: | Kostas Antonakis Ivan Chouroulinkov |
| |
| Affiliation: | Institut de Recherches Scientifiques sur le Cancer du CNRS 94 800 Villejuif, France |
| |
| Abstract: | The effect of 7- and 9- [(6′-deoxy-L-lyxo-hexosyl-2′ (and -4′)-ulose] purines on the growth of KB cells in vitro, was investigated. These keto-nucleosides are the first keto-hexosyl-purines shown to inhibit cellular growth in contrast to their inactive parent nucleosides. A significative difference in activity between 7- and 9-keto-nucleosides has been shown. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
