|
|||||
|
|
The multi‐kinase inhibitor TG02 overcomes signalling activation by survival factors to deplete MCL1 and XIAP and induce cell death in primary acute myeloid leukaemia cells |
|
| Authors: | Monica Pallis Amina Abdul‐Aziz Francis Burrows Claire Seedhouse Martin Grundy Nigel Russell |
| Institution: | 1. Nottingham University Hospitals, , Nottingham, UK;2. University of Nottingham, , Nottingham, UK;3. Tragara Pharmaceuticals, , San Diego, CA, USA |
| Abstract: | |
| Keywords: | TG02 acute myeloid leukaemia RNA Polymerase II MCL1 cytotoxicity |